Crystal Przybille resides in Kelowna, British Columbia. She has exhibited in Canada and Europe, and has received several grants for her work, including from Canada Council for the Arts and the BC Arts Council. She received the Okanagan Arts Award for Visual Art, 2012.

Przybille has participated in artist residency programs in British Columbia, Nunavut, and the Netherlands. She has created several public artworks, including The Father Pandosy Mission 150th Anniversary Commemorative Sculpture, The Hands of Time (the City of Victoria's 150th Anniversary Commemorative Sculpture) and Illuminature (City of Kelowna).

Her current project is a life sized, bronze figurative sculpture of Chief Sʷknc̓ut (Sookinchute), commissioned by Westbank First Nation.